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- 產品名稱： Sulfo-SMCC sodium
- 產品貨號： CST18728
- 貨期： 現(xiàn)貨
- 價格與訂購： 417
- 數(shù)量：
庫存： 5
- 規(guī)格： 10 mg
- 產品信息
- 如何訂購
產品名（Product Name）
Sulfo-SMCC sodium
貨號（Catalog No.）
CST18728
產品描述
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, non-cleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
The crosslinker Sulfo-SMCC consists of a maleimide and an N-hydroxysuccinimide ester group to bind to sulfhydryl groups and primary amines, respectively. Sulfo-SMCC inhibits the end-to-end annealing of stabilized Microtubules (MTs). MTs are treated with 250 μM Sulfo-SMCC, and imaged after incubation for 0 h, 6 h, and 24 h. MTs treated with Sulfo-SMCC shows a constant mean length, independent of the incubation time[1].
分子式
C16H17N2NaO9S
分子量
436.37
參考文獻
[1]Prabhune M, et al. Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro. PLoS One. 2016 Aug 25;11(8):e0161623.
儲存和溶解度
H2O:12 mg/mL (27.50 mM),Need ultrasonic
DMSO:125 mg/mL (286.45 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Note
For research use only .
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