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Glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells. Glofitamab is an investigational, T-cell bispecific antibody with a distinctive design that features 2 Fab arms for binding CD20 on B cells, along with 1 Fab arm for binding CD3 on T cells. The CD3 binding arm is fused directly to one of the CD20-binding arms in a head-to-tail fashion via a short flexible linker.icon

 CSD00634  

Humanized

Liquid

0.01M PBS, pH 7.4.

1 mg/ml

>95% 

Monoclonal

IgG1-kappa-lambda

Bispecific,B-lymphocyte surface antigen B1,Membrane-spanning 4-domains subfamily A member 1,MS4A1,Leukocyte surface antigen Leu-16,B-lymphocyte antigen CD20,Bp35,CD20,T3E,T-cell surface antigen T3/Leu-4 epsilon chain,CD3e,T-cell surface glycoprotein CD3 epsilon chain

Protein A or G purified from cell culture supernatant.

Please contact with the lab for this information.

Mammalian cells

P11836 & P07766

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

Bispecific, CD20-TCB (2:1), RG-6026, CAS: 2229047-91-8

For research use only .Not suitable for clinical or therapeutic use.