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- 產(chǎn)品名稱： Anti IDH1 Mouse Monoclonal Antibody
- 產(chǎn)品貨號： CS26136
- 貨期： 現(xiàn)貨
- 價格與訂購： 2800
- 數(shù)量：
庫存： 100
- 規(guī)格： 100μl 200μl
- 產(chǎn)品信息
- 如何訂購
Catalog Number
CS26136
Gene Symbol
IDH1
Description
Anti IDH1 Mouse Monoclonal Antibody
Background
Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Mutations of Arg-132 in IDH to Cys, His, Leu or Ser abolish magnesium binding and the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R-2-hydroxyglutarate. Elevated levels of R-2-hydroxyglutarate are correlated with an elevated risk of malignant brain tumors.
Immunogen
Recombinant proteins of human IDH1 (amino acids 1-240).
Applications
ELISA, WB, IHC, IP
Recommended Dilutions
ELISA: 1:1000-1:5000
WB: 1:100-1:1000
IHC: 1:50-1:100
Concentration
1 mg/ml
Host
mouse
Format
Liquid
Clonality
Monoclonal
Isotype
IgG
Purity
Purified from ascites
Preservative
no
Constituents
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity
Anti IDH1 antibody recognizes IDH1 of vertebrates.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles
Western blot
Western blot analysis of recombinant IDH1 protein. Purified His-tagged IDH1 protein (amino acids 1-240) (Cat.#10198) was blotted with anti IDH1 mouse antibody (Cat.# CS26136).
Note
For research use only .
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